Photoresponsive granular hydrogels for spatiotemporal control of matrix mechanics and MSC behavior
Friend, N. E., et al. Advanced Materials, 2026 (link)
Photoresponsive granular hydrogels enable dynamic, spatially defined control of matrix mechanics to direct cell behavior after scaffold assembly.
Biofabrication and characterization of vascularizing PEG-norbornene microgels
Friend, N. E., et al. JBMR-A, 2025 (link)
Synthetic PEG-norbornene microgels provide modular, tunable microenvironments that support the formation of robust and well-distributed microvascular networks.
Pre-cultured, cell-encapsulating fibrin microbeads for the vascularization of ischemic tissues
Friend, N. E., et al. JBMR-A, 2023 (link)
Prevascularized fibrin microbeads promote functional vascularization, tissue reperfusion, and limb salvage in a model of hindlimb ischemia.
A combination of matrix stiffness and degradability dictate microvascular network assembly and remodeling in cell-laden PEG hydrogels
Friend, N. E., et al. Biomaterials, 2023 (link)
Matrix stiffness and degradability act together to regulate microvascular network assembly, morphology, and remodeling in engineered 3D microenvironments.
Injectible pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivoÂ
Friend, N. E., et al. Scientific Reports, 2020 (link)
Prevascularized fibrin microbeads form extensive, perfused human microvascular networks following minimally invasive delivery in vivo.